Richard C. Pleus, Ph.D.
About
Richard C. Pleus, Ph.D., M.S., is a toxicologist whose work spans environmental and occupational health, with a focus on chemical exposure assessment and risk evaluation. His published research, appearing in journals such as Regulatory Toxicology and Pharmacology, Inhalation Toxicology, and Toxicology and Applied Pharmacology, addresses a range of substances and exposure scenarios, including perchlorate in drinking water and its effects on thyroid function, 1,4-dioxane carcinogenicity, lithium-ion battery fire emissions, cellulose insulation inhalation, and the risk assessment of nanomaterials. His work on perchlorate includes pooled analyses of iodine uptake thresholds and population-level exposure data drawn from NHANES surveillance.
In addition to his research activity, Dr. Pleus has provided expert declarations and testimony in regulatory and legal proceedings, including work submitted to the South Coast Air Quality Management District. His forensic work involves drafting expert reports and offering testimony on toxicological questions, making him active in both scientific and legal contexts where chemical exposure and health risk are at issue.
Credentials
Publications
- Exposure Assessment Study on Lithium-Ion Battery Fire in Explosion Test Room in Battery Testing Facility.
- Animal Welfare Considerations When Conducting OECD Test Guideline Inhalation and Toxicokinetic Studies for Nanomaterials.
- A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane.
- Repeated dose inhalation developmental toxicity study in rats exposed to cellulose insulation with boric acid additive.
- Environmental exposure to perchlorate: A review of toxicology and human health.
- Determination of Thresholds of Radioactive Iodine Uptake Response With Clinical Exposure to Perchlorate: A Pooled Analysis.
- Exposure of the US Population to Nitrate, Thiocyanate, Perchlorate, and Iodine Based on NHANES 2005-2014.
- Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.
- Reply to Response to: urinary nitrate, thiocyanate, and perchlorate and serum thyroid endpoints based on NHANES 2001 to 2002.
- A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment.
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