Madeleine J. Swortwood, Ph.D.
About
Dr. Madeleine J. Swortwood is a forensic toxicologist whose work centers on the detection and quantification of drugs and their metabolites in biological specimens. Her research addresses a wide range of substances, including synthetic opioids and fentanyl analogs, psychedelics such as psilocin and DMT, stimulants including methylphenidate and amphetamine, and opioid maintenance medications. She has also examined the pharmacokinetics of oxycodone and contributed to the analysis of alcohol biomarkers in biological fluids.
Her peer-reviewed publications, numbering more than 40, appear in journals including the Journal of Forensic Sciences, Journal of Analytical Toxicology, Drug Testing and Analysis, and Forensic Science International. Her methodological work frequently involves liquid chromatography-tandem mass spectrometry and related analytical techniques applied to matrices such as blood, urine, and oral fluid. One line of her published research examines drug exposure in the context of lactation, reflecting an interest in the intersection of forensic toxicology and clinical pharmacology.
Dr. Swortwood has been retained in forensic matters involving the interpretation of toxicological findings, including cases that require analysis of postmortem specimens, impaired driving, and drug facilitated crimes.
Publications
- Analysis of N,N-dimethyltryptamine (DMT) and its metabolites using LC-MS/MS for forensic purposes.
- Quantification of psilocin in human whole blood using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Buprenorphine-Naloxone Maintenance and Lactation.
- Review of analytical methods for screening and quantification of fentanyl analogs and novel synthetic opioids in biological specimens.
- Chiral separation and quantitation of methylphenidate, ethylphenidate, and ritalinic acid in blood using supercritical fluid chromatography.
- Evaluation of Alcohol Markers in Urine and Oral Fluid after Regular and Hard Kombucha Consumption.
- Analysis of methylphenidate, ethylphenidate, lisdexamfetamine, and amphetamine in oral fluid by liquid chromatography-tandem mass spectrometry.
- Urinary Pharmacokinetics of Immediate and Controlled Release Oxycodone and its Phase I and II Metabolites Using LC-MS-MS.
- Determination of morphine, codeine, and thebaine concentrations from poppy seed tea using magnetic carbon nanotubes facilitated dispersive micro-solid phase extraction and GC-MS analysis.
- Quantification of fentanyl analogs in oral fluid using LC-QTOF-MS.
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