About
Ethan Alden-Danforth is an organic chemist whose research focuses on asymmetric and bifunctional catalysis, with particular attention to enantioselective reactions and the synthesis of non-natural compounds. His work spans the development of cooperative Lewis acid/base systems, catalytic alpha-fluorination methods, and cycloaddition strategies employing chiral ammonium fluoride precatalysts.
His peer-reviewed publications have appeared in the Journal of the American Chemical Society, the Journal of Organic Chemistry, Organic Letters, and Accounts of Chemical Research, reflecting contributions across both synthetic methodology and mechanistic understanding. His published work includes studies on dual metal-ketene enolate activation, asymmetric approaches to non-natural alpha-amino acid derivatives, and the integration of asymmetric catalysis with natural product functionalization.
Publications
- Combining asymmetric catalysis with natural product functionalization through enantioselective alpha-fluorination.
- Catalytic, asymmetric alpha-fluorination of acid chlorides: dual metal-ketene enolate activation.
- Asymmetric cycloadditions of o-quinone methides employing chiral ammonium fluoride precatalysts.
- Bifunctional asymmetric catalysis: cooperative Lewis acid/base systems.
- An Asymmetric, bifunctional catalytic approach to non-natural alpha-amino acid derivatives.
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