Dan Marian Danila
About
Dr. Dan Marian Danila is a hospitalist physician practicing in Virginia. He holds licenses across multiple states, including Virginia, Maryland, Pennsylvania, Minnesota, Georgia, and South Dakota, reflecting a practice that extends across regional and institutional settings.
His published research, spanning more than 100 peer-reviewed works, covers a notably broad range of clinical topics. A significant portion of his publications addresses oncology, particularly metastatic castration-resistant prostate cancer, including work on androgen receptor splice variants, PARP inhibition, genomic predictors of treatment response, and the role of BCL2 in castration resistance. These studies have appeared in journals such as JCO Precision Oncology, Prostate Cancer and Prostatic Diseases, and Investigational New Drugs. His research also includes pediatric cases, among them management of blunt pancreatic trauma and extreme hypertriglyceridemia with recurrent pancreatitis, published in Pediatric Reports and the Journal of Clinical Medicine. Additional work has examined biomaterial topics including cellular mechanosensing at implant interfaces and liposome-based imaging of inflammation in bone implants.
Credentials
Publications
- Cytoplasmic versus nuclear localization of androgen receptor splice variant 7 as a predictor of benefit from androgen receptor pathway inhibitors in metastatic castration-resistant prostate cancer (PROPHECY trial).
- Isolated Blunt Pancreatic Head Injury with Evolving Acute Peripancreatic Fluid Collection in a Child Successfully Managed Conservatively.
- Genomic Features and Response to Poly(ADP-ribose) Polymerase Inhibition in Metastatic Castration-Resistant Prostate Cancer.
- Multimodal Management of Extreme Hypertriglyceridemia in a Child with Recurrent Pancreatitis: Clinical Challenges and Solutions.
- A phase 1b/2 study of intermittent talazoparib plus temozolomide in patients with metastatic castration-resistant prostate cancer and no mutations in DNA damage response genes.
- Sensing the Stiffness: Cellular Mechano-Sensing at the Implant Interface.
- Liposomes as Imaging Agents of Inflammation and Oxidative Stress in Bone Implants.
- BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways.
- Severity and Clinical Outcomes of Pediatric Burns-A Comprehensive Analysis of Influencing Factors.
- Clinical, Imaging, and Technical Factors Associated with Successful Genomic Profiling of Bone Biopsy Tissue in Prostate Cancer.
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